Okay, that's of course if MLP gets season 7 and beyond...
But what things would you want to see, but are probably not going to happen? Let's keep it more realistic and exclude what's definitely impossible.
For example, I'd like to see an episode focused Flurry Heart getting a Cutie Mark (and finding her place). Why do I think it's unlikely? Well, I just don't think they'd make a timeskip like that. I mean, Pound and Pumpkin Cake are still toddlers, and I feel like they won't get into CM-receiving age anytime soon. Therefore Flurry growing sufficiently old anytime soon is probably not happening. Not to mention, the CMC would have to grow up as well.
Now, your turn.