From favorite to least favorite, between Nightmare Moon, Discord, Queen Chrysalis, King Sombra, Sunset Shimmer, and the black vines, and, if you wish, Ahuizotl, Mane-iac, and Windigos? And if you want, you can list Sunset Shimmer and her demon form separately, since they're entirely different types of villain.
For me, it's...
- Queen Chrysalis
- King Sombra
- Nightmare Moon
- Demon Sunset Shimmer
- Sunset Shimmer
I almost want to tie Discord with Nightmare Moon
Minor antagonists who are more of jerks are not listed here. Recently added Trixie, I make an exception for her since she goes from jerk to evil when corrupted.
By request here's a poll: Of all the main villains, major villains, and minor villains just as evil as any of the main villains, who is your most favorite? (Updated the poll to include the Tatzlwurm, the Chimera, Garble, and Tirek, as well as some of the earlier monsters that try to kill the heroes)
If you still want to see the results of the older poll... Here is is below.